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Chemistry - Biomolecules

Practise 218 JEE Main previous year questions on Biomolecules, compiled from papers spanning 2002 to 2026. Each question is pulled directly from the actual exam paper it appeared in, so you're practising in the exact style and difficulty JEE Main tests.

Biomolecules has been asked in 25 of the 25 years of JEE Main papers analysed (2002–2026), with 218 questions in all. 48% of them were easy, 41% moderate and 11% tough. Most of its questions came from 2021, with 29 questions that year. In the last three years (2024–2026) it had 54 questions across 49 papers, about 1.1 per paper.

The chapter's 8 topics are not weighted equally: Properties and Preparation of Amino Acids (43 questions, 20%), Proteins (41 questions, 19%), and Disaccharides and Polysaccharides (34 questions, 16%) have been asked the most. Over the last five years the most frequent topics have been Proteins (24), Properties and Preparation of Amino Acids (21), and Carbohydrates (17). Properties and Preparation of Amino Acids has produced the most tough questions (7).

  1. 1The incorrect statement from the following with respect to carbohydrates is:08 Apr, 2026 (E)Carbohydrates
  2. 2Which of the following amino acid will give violet coloured complex with neutral ferric chloride solution?08 Apr, 2026 (E)Proteins
  3. 3Match the LIST-I with LIST-II List-I Deficiency Disease List-II Vitamin A. Scurvy I. Pyridoxine B. Convulsions II. Vitamin A C. Cheilosis II06 Apr, 2026 (M)Vitamins
  4. 4Match the LIST-I with LIST-II List-I Amino acid List-II Positive reaction/Test for functional group present in side chain of amino acid A. G06 Apr, 2026 (M)Properties and Preparation of Amino Acids
  5. 5Sucrose hydrolyses in acidic medium into glucose and fructose by first order rate law with hour. The percentage of sucrose remaining after h06 Apr, 2026 (M)Disaccharides and Polysaccharides
  6. 6Consider the following reactions. Total number of electrons in the bonds and lone pair of electrons in the product is :06 Apr, 2026 (E)Preparation and Reactions of Glucose
  7. 7Identify the correct statements. A. Glucose exists in two anomeric forms. B. Anomers of glucose differ in configuration at C in cyclic hemia05 Apr, 2026 (M)Carbohydrates
  8. 8Identify the incorrect statement about tertiary structure of proteins.05 Apr, 2026 (E)Proteins
  9. 9Given below are two statements : Statement I: The two cyclic forms of D-(+)-glucose (α and β anomers differing at C1 hydroxyl orientation) a05 Apr, 2026 (E)Carbohydrates
  10. 10Given below are two statements: Statement I: The structure of Maltose is given below: Maltose is a non-reducing sugar. Statement II: The str04 Apr, 2026 (M)Disaccharides and Polysaccharides
  11. 11Match the LIST-I with LIST-II List-I Name of amino acid List-II One letter symbol/type A. Arginine I. D/Non-essential B. Aspartic acid II. R04 Apr, 2026 (M)Properties and Preparation of Amino Acids
  12. 12A D-aldotetrose on oxidation with concentrated resulted in optically inactive dicarboxylic acid. The structure of the D-aldotetrose is:04 Apr, 2026 (E)Carbohydrates
  13. 13Match List - I with List - II. List - I Vitamin List - II Name A. Vitamin I. Pyridoxine B. Vitamin II. Ascorbic acid C. Vitamin III. Thiamin02 Apr, 2026 (M)Vitamins
  14. 14Identify the correct pair having amino acid (A) and the hormone (B) that is iodinated derivative of the amino acid (A). (T and Y represent o02 Apr, 2026 (E)Properties and Preparation of Amino Acids
  15. 15In the given pentapeptide, find out an essential amino acid and the sequence present in the pentapeptide: Choose the correct answer from the28 Jan, 2026 (M)Properties and Preparation of Amino Acids
  16. 16Structures of four disaccharides are given below. Among the given disaccharides, the non-reducing sugar is :28 Jan, 2026 (E)Disaccharides and Polysaccharides
  17. 17A student is given one compound among the following compounds that gives positive test with Tollen's reagent. The compound is :24 Jan, 2026 (M)Carbohydrates
  18. 18The number of possible tripeptides formed involving alanine (ala), glycine (gly) and valine (val), where no amino acid has been used more th24 Jan, 2026 (E)Proteins
  19. 19From the given following (A to D) cyclic structures, those which will not react with Tollen's reagent are :23 Jan, 2026 (M)Preparation and Reactions of Glucose
  20. 20Both human DNA and RNA are chiral molecules. The chirality in DNA and RNA arises due to the presence of23 Jan, 2026 (E)Nucleic Acids
  21. 21Given below are two statements: Statement I : Sucrose is dextrorotatory. However, sucrose upon hydrolysis gives a solution having mixture of22 Jan, 2026 (M)Preparation and Properties of Monohalides
  22. 22Match List - I with List - II. Choose the correct answer from the options given below :22 Jan, 2026 (E)Preparation and Reactions of Glucose
  23. 23Identify the correct statements. A. Arginine and Tryptophan are essential amino acids. B. Histidine does not contain heterocyclic ring in it21 Jan, 2026 (M)Properties and Preparation of Amino Acids
  24. 24The correct statements are : A. Activation energy for enzyme catalysed hydrolysis of sucrose is lower than that of acid catalysed hydrolysis21 Jan, 2026 (E)Proteins
  25. 25Choose the correct option for structures of A and , respectively.08 Apr, 2025 (E)Nucleic Acids
  26. 26Given below are two statements: Statement I : D-(+)-glucose fructose sucrose Statement II : Invert sugar is formed during sucrose hydrolysis07 Apr, 2025 (M)Disaccharides and Polysaccharides
  27. 27Given below are two statements : Statement (I) : On hydrolysis, oligo peptides give rise to fewer number of -amino acids while proteins give07 Apr, 2025 (E)Proteins
  28. 28Identify the pair of reactants that upon reaction, with elimination of HCl will give rise to the dipeptide Gly-Ala.04 Apr, 2025 (M)Proteins
  29. 29The total number of hydrogen bonds of a DNA-double Helix strand whose one strand has the following sequence of bases is_______. - G - G-C-A-04 Apr, 2025 (M)Nucleic Acids
  30. 30A dipeptide, " " on complete hydrolysis gives " " and " ". " " on treatment with aq. produces lactic acid. On the other hand " " on heating 04 Apr, 2025 (E)Proteins
  31. 31Which of the following is the correct structure of L-fructose?03 Apr, 2025 (M)Carbohydrates
  32. 32Fat soluble vitamins are : A. Vitamin B. Vitamin C C. Vitamin E D. Vitamin E. Vitamin K Choose the correct answer from the options given bel03 Apr, 2025 (E)Vitamins
  33. 33Given below are two statements : Statement I : Wet cotton clothes made of cellulose based carbohydrate takes comparatively longer time to ge03 Apr, 2025 (E)Disaccharides and Polysaccharides
  34. 34Identify the correct statement among the following:02 Apr, 2025 (M)Properties and Preparation of Amino Acids
  35. 35A tetrapeptide " " on complete hydrolysis produced glycine (Gly), alanine (Ala), valine (Val), leucine (Leu) in equimolar proportion each. T02 Apr, 2025 (E)Properties and Preparation of Amino Acids
  36. 36Match List - I with List - II. \( {array}{ll|ll} & {array}{l} { List - I } \\ { (Carbohydrate) } {array} & {array}{l} { List - II } \\ { (Li29 Jan, 2025 (M)Preparation and Reactions of Glucose
  37. 37Identify the essential amino acids from below : (A) Valine (B) Proline (C) Lysine (D) Threonine (E) Tyrosine Choose the correct answer from 29 Jan, 2025 (E)Properties and Preparation of Amino Acids
  38. 38Given below are two statements: Statement I : D-glucose pentaacetate reacts with 2, 4-dinitrophenylhydrazine Statement II : Starch, on heati28 Jan, 2025 (M)Preparation and Reactions of Glucose
  39. 39Match List - I with List - II. Choose the correct answer from the options given below :28 Jan, 2025 (E)Preparation and Reactions of Glucose
  40. 40Identify correct conversion during acidic hydrolysis from the following : (A) starch gives galactose. (B) cane sugar gives equal amount of g28 Jan, 2025 (E)Disaccharides and Polysaccharides
  41. 41The carbohydrate "Ribose" present in DNA, is A. A pentose sugar B. present in pyranose from C. in "D" configuration D. a reducing sugar, whe24 Jan, 2025 (M)Carbohydrates
  42. 42Choose the correct answer from the options given below :24 Jan, 2025 (E)Nucleic Acids
  43. 43Given below are two statements: Statement I: Fructose does not contain an aldehydic group but still reduces Tollen's reagent Statement II: I23 Jan, 2025 (M)Carbohydrates
  44. 44The -Helix and - Pleated sheet structures of protein are associated with its :23 Jan, 2025 (E)Proteins
  45. 45Which of the following acids is a vitamin?22 Jan, 2025 (M)Vitamins
  46. 46Identify the number of structure/s from the following which can be correlated to D-glyceraldehyde.22 Jan, 2025 (E)Preparation and Reactions of Glucose
  47. 47Total number of essential amino acid among the given list of amino acids is _______ Arginine, Phenylalanine, Aspartic acid, Cysteine, Histid09 Apr, 2024 (M)Properties and Preparation of Amino Acids
  48. 48The incorrect statement about Glucose is :09 Apr, 2024 (E)Carbohydrates
  49. 49The incorrect statement regarding the given structure is08 Apr, 2024 (M)Preparation and Reactions of Glucose
  50. 50The total number of carbon atoms present in tyrosine, an amino acid, is _______08 Apr, 2024 (E)Properties and Preparation of Amino Acids

Frequently Asked Questions

1.How many questions are available for Biomolecules?

This chapter includes 218 questions compiled from JEE Main papers spanning 2002 to 2026.

2.Are these questions only from JEE Main, or from other exams too?

These are JEE Main questions specifically for the Biomolecules chapter. Questions from other exams like NTA Abhyas (JEE Main) or JEE Advanced are organised separately under their respective exam sections.

3.Is Biomolecules an important chapter for JEE Main Chemistry?

Biomolecules has appeared in 25 of the 25 years of JEE Main papers covered here, with 218 questions across 185 papers - about one per paper it appears in.

4.What is the difficulty level of Biomolecules questions in JEE Main?

Of the 218 questions analysed for this chapter, 48% are easy, 41% moderate and 11% tough. 2021 had the most, with 29 questions.

5.Which topics in Biomolecules should I focus on?

These topics have carried the most weightage in Biomolecules:

  • Properties and Preparation of Amino Acids - 43 questions (20%)
  • Proteins - 41 questions (19%)
  • Disaccharides and Polysaccharides - 34 questions (16%)
  • Properties and Preparation of Amino Acids has produced the most tough questions (7).
6.Is Biomolecules's weightage in JEE Main going up or down?

Across all 185 papers analysed, Biomolecules has averaged about 1.2 questions per paper. In the last three years (2024–2026), that average has stayed about the same, at about 1.1 questions per paper. Use the year-wise numbers on this page for the exact trend before you decide how much time to give it.