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Chemistry - Biomolecules

Practise 73 COMEDK previous year questions on Biomolecules, compiled from papers spanning 2012 to 2026. Each question is pulled directly from the actual exam paper it appeared in, so you're practising in the exact style and difficulty COMEDK tests.

Biomolecules has been asked in 15 of the 15 years of COMEDK papers analysed (2012–2026), with 73 questions in all. 56% of them were easy, 38% moderate and 5% tough. Most of its questions came from 2025, with 13 questions that year. In the last three years (2024–2026) it had 31 questions across 10 papers, about 3.1 per paper.

The chapter's 8 topics are not weighted equally: Properties and Preparation of Amino Acids (12 questions, 16%), Nucleic Acids (11 questions, 15%), and Proteins (10 questions, 14%) have been asked the most. Over the last five years the most frequent topics have been Vitamins (9), Carbohydrates (7), and Preparation and Reactions of Glucose (7). Fats has produced the most tough questions (1).

  1. 1The secondary structure of protein consists of:09 May, 2026 (S1)Proteins
  2. 2Which among the following is an INCORRECT statement?09 May, 2026 (S1)Carbohydrates
  3. 3Which of the following is a correct match?09 May, 2026 (S1)Nucleic Acids
  4. 4Identify the correct statement.09 May, 2026 (S2)Preparation and Reactions of Glucose
  5. 5A small segment of a polypeptide gave on complete hydrolysis 3 molecules of alanine, 2 molecules of glycine and 3 molecules of cysteine. Wha09 May, 2026 (S2)Proteins
  6. 6Match the characteristic from Col. I with the Vitamins given in Col. II. Characteristics Vitamins A Water soluble that is not excreted easil09 May, 2026 (S2)Vitamins
  7. 7A polysaccharide represented as n serves as a reserve carbohydrate in human beings. An enzyme Phosphorylase breaks it down to glucose when r25 May, 2025 (Shift)Disaccharides and Polysaccharides
  8. 8Which of the following statement/s about nucleic acids is/are correct? i. The chirality of both DNA and RNA molecules is due to the L-sugar 25 May, 2025 (Shift)Nucleic Acids
  9. 9Which statement is incorrect about aminoacids?25 May, 2025 (Shift)Properties and Preparation of Amino Acids
  10. 10Match the reactions of Glucose given in Column I with the major product formed in the reaction as in Column II. Column I - Reactions Column 10 May, 2025 (S1)Preparation and Reactions of Glucose
  11. 11Two statements, one Assertion (A) and the other Reason (R) are given. Choose the correct option. Assertion: 2-aminoethanoic acid and p-amino10 May, 2025 (S1)Properties and Preparation of Amino Acids
  12. 12Two statements, one Assertion (A) and the other Reason (R) are given. Choose the correct option. Assertion: Maltose, a disaccharide, is a re10 May, 2025 (S1)Disaccharides and Polysaccharides
  13. 13Choose the incorrect statement.10 May, 2025 (S1)Proteins
  14. 14Which one of the following is the correct statement?10 May, 2025 (S2)Carbohydrates
  15. 15Match and D with the appropriate functions given. \( {array}{|l|l|l|l|} & { Column I } & & { Functions } \\ { A } & { Oxidoreductase } & { P10 May, 2025 (S2)Nucleic Acids
  16. 16Imagine a pentapeptide molecule having a total of one , , group each and two groups. If the pH is maintained at 13.2, what would be the tota10 May, 2025 (S2)Properties and Preparation of Amino Acids
  17. 17Which of the following is a water soluble vitamin?10 May, 2025 (S3)Vitamins
  18. 18Identify the correct statement.10 May, 2025 (S3)Carbohydrates
  19. 19Two statements, one Assertion and the other Reason are given. Choose the right option. Assertion: Insulin is called a protein whereas Glycyl10 May, 2025 (S3)Proteins
  20. 20With reference to vitamins and its deficiency diseases, the correct statements are: (i) Cheilosis is due to the deficiency of Riboflavin (ii2024 (Afternoon Shift)Vitamins
  21. 21Which of the following statement is not true about glucose?2024 (Afternoon Shift)Preparation and Reactions of Glucose
  22. 22Among the following peptides, identify the pair where the name and its structure are correctly matched.2024 (Afternoon Shift)Proteins
  23. 23Two statements, Assertion and Reason are given. Choose the correct option from the following. Assertion: In the secondary structure of RNA, 2024 (Evening Shift)Nucleic Acids
  24. 24Match the Vitamins given in Column I with the diseases caused by their deficiency as given in Column II. No. Vitamin No. Deficiency A K P Ch2024 (Evening Shift)Vitamins
  25. 25Given are 4 statements related to the chemical properties of Glucose. Identify the two incorrect statements from the following. A. It reacts2024 (Evening Shift)Preparation and Reactions of Glucose
  26. 26Which of the following acid is a vitamin?2024 (Memory Based)Vitamins
  27. 27The segment of DNA which acts as the instruction manual for the synthesis of the protein is2024 (Memory Based)Nucleic Acids
  28. 28Which amino acid has phenolic OH group as its backbone?2024 (Memory Based)Properties and Preparation of Amino Acids
  29. 29Match the Hormones listed in Column I with their characteristics listed in Column II No. Hormone No. Characteristics A Adrenal Cortex P Medi2024 (Morning Shift)Vitamins
  30. 30Identify the 2 chemical tests which is not answered by Glucose having an open chain structure [A] Reaction with Schiff's reagent and with So2024 (Morning Shift)Carbohydrates
  31. 31Given below are 4 statements about Insulin. Which of these statement/(s) is/are correct? [A] Insulin is a globular protein consisting of 51 2024 (Morning Shift)Proteins
  32. 32One among the 4 Vitamins belonging to Complex, can be stored in our body. Identify the Vitamin.2023 (Evening Shift)Vitamins
  33. 33Choose the incorrect statement regarding Cellulose.2023 (Evening Shift)Disaccharides and Polysaccharides
  34. 34Structures of 3 Monosaccharides are given below. Two of them are Anomers. Identify the two Anomers.2023 (Evening Shift)Carbohydrates
  35. 35Which of the following hexoses will form the same osazone when treated with excess phenyl hydrazine?2023 (Memory Based)Preparation and Reactions of Glucose
  36. 36Pick out the incorrect statement(s) from the following. 1. Glucose exists in two different crystalline forms, -D-glucose and -D-glucose. 2. 2023 (Memory Based)Carbohydrates
  37. 37Which one of the following is an important component of chlorophyll?2023 (Morning Shift)Vitamins
  38. 38Which of the following hexoses will form the same osazone when treated with excess phenyl hydrazine?2023 (Morning Shift)Preparation and Reactions of Glucose
  39. 39Pick out the incorrect statement(s) from the following. 1. Glucose exists in two different crystalline forms, -D-glucose and -D-glucose. 2. 2023 (Morning Shift)Carbohydrates
  40. 40The monosaccharides of maltose is2022Disaccharides and Polysaccharides
  41. 41The essential amino acid are (i) Leucine (ii) Glutamic acid (iii) Asparagine (iv) Valine correct option is2022Properties and Preparation of Amino Acids
  42. 42On treatment of glucose with bromine water the product formed is2022Preparation and Reactions of Glucose
  43. 43Which of the following vitamin is responsible for beri-beri disease?2022Vitamins
  44. 44Which one of the following sets of monosaccharides forms sucrose?2021Preparation and Reactions of Glucose
  45. 45Which of the following amino acid contains polar group?2021Properties and Preparation of Amino Acids
  46. 46Among the following enzymes, which one is involved in the given below catalytic reaction?2021Disaccharides and Polysaccharides
  47. 47Xerophthalmia disease causes by which deficiency of vitamin?2021Vitamins
  48. 48The amino acid which is not optically active is2020Properties and Preparation of Amino Acids
  49. 49Sucrose is a non-reducing sugar due to2019Disaccharides and Polysaccharides
  50. 50Sulphur containing amino acid is2019Properties and Preparation of Amino Acids

Frequently Asked Questions

1.How many questions are available for Biomolecules?

This chapter includes 73 questions compiled from COMEDK papers spanning 2012 to 2026.

2.Are these questions only from COMEDK, or from other exams too?

These are COMEDK questions specifically for the Biomolecules chapter. Questions from other exams like JEE Main or NTA Abhyas (JEE Main) are organised separately under their respective exam sections.

3.Is Biomolecules an important chapter for COMEDK Chemistry?

Biomolecules has appeared in 15 of the 15 years of COMEDK papers covered here, with 73 questions across 24 papers - about 3 per paper it appears in.

4.What is the difficulty level of Biomolecules questions in COMEDK?

Of the 73 questions analysed for this chapter, 56% are easy, 38% moderate and 5% tough. 2025 had the most, with 13 questions.

5.Which topics in Biomolecules should I focus on?

These topics have carried the most weightage in Biomolecules:

  • Properties and Preparation of Amino Acids - 12 questions (16%)
  • Nucleic Acids - 11 questions (15%)
  • Proteins - 10 questions (14%)
  • Fats has produced the most tough questions (1).
6.Is Biomolecules's weightage in COMEDK going up or down?

Across all 24 papers analysed, Biomolecules has averaged about 3.0 questions per paper. In the last three years (2024–2026), that average has stayed about the same, at about 3.1 questions per paper. Use the year-wise numbers on this page for the exact trend before you decide how much time to give it.