Q14 / 180 · COMEDK 2025 (10 May Shift 2) · Chemistry

Match $\mathrm{A}, \mathrm{B}, \mathrm{C}$ and D with the appropriate functions given. \(\begin{array}{|l|l|l|l|} \hline & \text { Column I } & & \text { Functions } \\ \hline \text { A } & \text { Oxidoreductase } & \text { P } & \text { Malfunctioning leads to Addison's disease. } \\ \hline \text { B } & \text { Phosphodiester bonds } & \text { Q } & \text { Regulates responses to external stimuli. } \\ \hline \text { C } & \text { Adrenal cortex } & \text { R } & \text { Catalyses glycolysis. } \\ \hline \text { D } & \text { Epinephrine. } & \text { S } & \text { Links nucleotides together. } \\ \hline \end{array}\)

  • Correct answer
    A
    $\mathrm{A}=\mathrm{R} \quad \mathrm{B}=\mathrm{S} \quad \mathrm{C}=\mathrm{P} \quad \mathrm{D}=\mathrm{Q}$
  • B
    $\mathrm{A}=\mathrm{Q} \quad \mathrm{B}=\mathrm{R} \quad \mathrm{C}=\mathrm{S} \quad \mathrm{D}=\mathrm{P}$
  • C
    $\mathrm{A}=\mathrm{R} \quad \mathrm{B}=\mathrm{S} \quad \mathrm{C}=\mathrm{Q} \quad \mathrm{D}=\mathrm{P}$
  • D
    $\mathrm{A}=\mathrm{R} \quad \mathrm{B}=\mathrm{P} \quad \mathrm{C}=\mathrm{S} \quad \mathrm{D}=\mathrm{Q}$

Solution

Oxidoreductases are enzymes that catalyze oxidation-reduction reactions. In the context of metabolic pathways like glycolysis, enzymes such as glyceraldehyde-3-phosphate dehydrogenase act as oxidoreductases. Thus, A matches with R.

Phosphodiester bonds are the covalent linkages that connect the 3' carbon atom of one sugar molecule and the 5' carbon atom of another in the sugar-phosphate backbone of DNA and RNA. Thus, B matches with S.

The adrenal cortex is an endocrine gland that produces essential hormones like cortisol and aldosterone. Malfunctioning or deficiency of the adrenal cortex leads to Addison's disease. Thus, C matches with P.

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter that prepares the body for fight-or-flight responses, effectively regulating responses to external stimuli. Thus, D matches with Q.

Combining these, we get A=R, B=S, C=P, D=Q.

Answer: $\mathrm{A}=\mathrm{R} \quad \mathrm{B}=\mathrm{S} \quad \mathrm{C}=\mathrm{P} \quad \mathrm{D}=\mathrm{Q}$

Hence, the correct answer is option: 'A'.

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