Q50 / 180 · COMEDK 2024 (Morning Shift) · Chemistry

Given below are 4 statements about Insulin. Which of these statement/(s) is/are correct? [A] Insulin is a globular protein consisting of 51 Amino acids. [B] Insulin is constituted of 3 polypeptide chains linked together. [C] Insulin is constituted of 2 polypeptide chains linked together by disulphide bonds. [D] The 3 polypeptide chains in Insulin are linked together by Hydrogen bonding.

  • Correct answer
    A
    [A] & [C]
  • B
    [D]
  • C
    [B]
  • D
    [B] & [D]

Solution

Insulin is a peptide hormone produced by the beta cells of the pancreatic islets. It is a globular protein composed of 51 amino acids. Therefore, statement [A] is correct.

Insulin consists of two polypeptide chains, known as the A-chain and the B-chain. The A-chain contains 21 amino acids, and the B-chain contains 30 amino acids. These two chains are linked together by two inter-chain disulphide bonds, and there is also an intra-chain disulphide bond within the A-chain. Therefore, statement [C] is correct, while statement [B] and statement [D] are incorrect.

Answer: [A] & [C]

Hence, the correct answer is option: 'A'.

Relevant Questions