Q27 / 200 · MHT CET - Medical 2026 (26 April Shift 1) · Biology

Originally, restriction endonucleases (REN) are named so because they __________

  • A
    restrict DNA replication in host bacterium.
  • B
    cut the DNA strands at specific restriction site.
  • Correct answer
    C
    destroy viral DNA to restrict the potential growth of virus in bacteria.
  • D
    restrict the translocation of viral DNA to prevent viral protein formation.

Solution

In 1963, two enzymes responsible for restricting the growth of bacteriophage in Escherichia coli were isolated. One of these added methyl groups to DNA, while the other cut DNA. The latter was called restriction endonuclease.

The term restriction refers to the function of these enzymes in restricting the potential growth and multiplication of bacteriophages (viruses) within the host bacterium by cleaving the viral DNA.

Answer: destroy viral DNA to restrict the potential growth of virus in bacteria.

Hence, the correct answer is option: 'C'.

More Biotechnology - Principles and Processes Questions