Q21 / 200 · MHT CET - Medical 2026 (25 April Shift 2) · Biology
Which one of the following characters does NOT belong to Down's Syndrome?
- AMild to moderate mental retardation
- Correct answerBChange in size and shape of RBCs
- COpen mouth, protruding tongue, flat nose
- DPoor skeletal development
Solution
Down's syndrome is a genetic disorder caused by the presence of an additional copy of chromosome 21 (trisomy of 21).
The affected individual is short-statured with a small round head, furrowed tongue, and partially open mouth. Physical, psychomotor, and mental development is retarded, leading to mild to moderate mental retardation and poor skeletal development.
Change in the size and shape of RBCs is a characteristic feature of sickle cell anemia, not Down's syndrome.
Answer: Change in size and shape of RBCs
The affected individual is short-statured with a small round head, furrowed tongue, and partially open mouth. Physical, psychomotor, and mental development is retarded, leading to mild to moderate mental retardation and poor skeletal development.
Change in the size and shape of RBCs is a characteristic feature of sickle cell anemia, not Down's syndrome.
Answer: Change in size and shape of RBCs
Hence, the correct answer is option: 'B'.