Q195 / 200 · NEET 2023 (Manipur) · Zoology
Select incorrect statement, regarding chemical structure of insulin.
- AC-peptide is not present in mature insulin molecule.
- BPolypeptide chains A and B are linked by disulphide bridges.
- Correct answerCMature insulin molecule consists of three polypeptide chains - A, B and C.
- DInsulin is synthesized as prohormone which contains extra stretch of C-peptide.
Solution
Option (3) is the answer because mature insulin does not contain C-peptide chain which is removed during maturation of pro-insulin into insulin. So, it contains only two polypeptide chains $\mathrm{A}$ and $\mathrm{B}$.
Option (1) is not the answer because C-peptide is absent in mature insulin molecule.
Option (2) is not the answer because polypeptide chains A and B are linked disulphide bridges.
Option (4) is not the answer because an extra stretch C-peptide is not present in mature insulin but present in pro-insulin.
Hence, the correct answer is option: 'C'.