Q11 / 59 · NEST (NISER) 2018 · Biology
Khorana performed experiments to decipher the codons that code for a particular amino acid. The results of these experiments using synthetic mRNAs and the corresponding polypeptide repeats that were generated are given in the table below.
$\begin{array}{|l|l|}\hline \text{Synthetic mRNAs} & \text{Polypeptide(s) synthesized} \\ \hline \hline(\text {CAA})_n & (\text {Thr-Thr})_n \text{ and } (\text {Asn-Asn})_n \text{ and } (\text {Gln-Gln})_n \\ \hline(\text {UUC})_n & (\text {Ser-Ser})_n \text{ and } (\text {Leu-Leu})_n \text{ and } (\text {Phe-Phe})_n \\ \hline(\text {UAC})_n & (\text {Thr-Thr})_n \text{ and } (\text {Leu-Leu})_n \text{ and } (\text {Tyr-Tyr})_n \\ \hline(\text {UUAC})_n & (\text {Leu-Leu-Thr-Tyr})_n \\ \hline\end{array}$
Based on the results, the correct combination(s) of codons and amino acids is/are
$\begin{array}{|l|l|}\hline \text{Synthetic mRNAs} & \text{Polypeptide(s) synthesized} \\ \hline \hline(\text {CAA})_n & (\text {Thr-Thr})_n \text{ and } (\text {Asn-Asn})_n \text{ and } (\text {Gln-Gln})_n \\ \hline(\text {UUC})_n & (\text {Ser-Ser})_n \text{ and } (\text {Leu-Leu})_n \text{ and } (\text {Phe-Phe})_n \\ \hline(\text {UAC})_n & (\text {Thr-Thr})_n \text{ and } (\text {Leu-Leu})_n \text{ and } (\text {Tyr-Tyr})_n \\ \hline(\text {UUAC})_n & (\text {Leu-Leu-Thr-Tyr})_n \\ \hline\end{array}$
Based on the results, the correct combination(s) of codons and amino acids is/are
- AACU - Leu; UUA - Thr; ACU - Tyr
- Correct answerBCUU - Leu; ACA - Thr; UAC - Tyr
- CUAC - Leu; CUU - Thr; ACU - Tyr
- Correct answerDUUA - Leu; ACU - Thr; UAC - Tyr
Hence, the correct answer is options: 'B', 'D'.