Identify the INCORRECT statement with respect to enzymatic activity.

Enzymes generally function in a narrow range of temperature and pH. Each enzyme shows its highest activity at a particular temperature called the optimum temperature. Activity declines both below and above the optimum value.

Low temperature preserves the enzyme in a temporarily inactive state, whereas high temperature destroys enzymatic activity because proteins are denatured by heat. Therefore, the activity of enzymes is not increased at low temperatures.

Increase in substrate concentration increases the velocity of enzyme activity until it reaches a maximum velocity ($V_{max}$).

$K_m$ (Michaelis constant) is a constant and a characteristic feature of a given enzyme for a specific substrate.

The rate of reaction increases with an increase in enzyme concentration, provided the substrate concentration is not limiting.

Answer: The activity of enzymes is increased at low temperature.