Q13 / 200 · MHT CET - Medical 2026 (21 April Shift 1) · Biology
Given below are two statements:
Statement (I): In rDNA technology, the transformation process generates a mixed population of transformed and non-transformed host cells.
Statement (II): In the screening process, both transformed and non-transformed host cells divide and redivide along with the replication of recombinant DNA.
In light of the above statements, choose the most appropriate answer from the options given below.
Statement (I): In rDNA technology, the transformation process generates a mixed population of transformed and non-transformed host cells.
Statement (II): In the screening process, both transformed and non-transformed host cells divide and redivide along with the replication of recombinant DNA.
In light of the above statements, choose the most appropriate answer from the options given below.
- ABoth Statement (I) and Statement (II) are correct.
- BBoth Statement (I) and Statement (II) are incorrect.
- Correct answerCStatement (I) is correct but Statement (II) is incorrect.
- DStatement (I) is incorrect but Statement (II) is correct.
Solution
Statement (I) is correct because the transformation process is not highly efficient, resulting in a mixed population of both transformed and non-transformed host cells.
Statement (II) is incorrect because the screening process involves the use of selectable markers (such as antibiotic resistance genes) which selectively permit the growth and division of only the transformed cells while eliminating or preventing the growth of non-transformed cells. Thus, non-transformed cells do not divide and redivide during screening.
Answer: Statement (I) is correct but Statement (II) is incorrect.
Statement (II) is incorrect because the screening process involves the use of selectable markers (such as antibiotic resistance genes) which selectively permit the growth and division of only the transformed cells while eliminating or preventing the growth of non-transformed cells. Thus, non-transformed cells do not divide and redivide during screening.
Answer: Statement (I) is correct but Statement (II) is incorrect.
Hence, the correct answer is option: 'C'.