Q55 / 200 · MHT CET - Medical 2026 (25 April Shift 2) · Biology

Given below are two statements.
Statement I - Prothrombinase converts inactive prothrombin into active thrombin.
Statement II - Thrombin converts insoluble fibrinogen into soluble fibrin.
In the light of above statements, select the correct option given below:

  • A
    Both statement I and statement II are correct
  • B
    Both statement I and statement II are incorrect
  • Correct answer
    C
    Statement I is correct but statement II is incorrect
  • D
    Statement I is incorrect but statement II is correct

Solution

Statement I is correct because the enzyme complex prothrombinase (also known as thrombokinase) catalyzes the conversion of the inactive plasma protein prothrombin into the active enzyme thrombin during the blood coagulation cascade.

Statement II is incorrect because thrombin converts soluble fibrinogen into insoluble fibrin strands, which form a meshwork to trap blood cells and create a clot. The statement incorrectly reverses their solubility, stating that fibrinogen is insoluble and fibrin is soluble.

Therefore, Statement I is correct but Statement II is incorrect.

Answer: Statement I is correct but statement II is incorrect

Hence, the correct answer is option: 'C'.

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