Q196 / 200 · NEET 2022 (Phase 1) · Zoology

Given below are two statements:

Statement I: Restriction endonucleases recognise specific sequence to cut DNA known as palindromic nucleotide sequence.

Statement II: Restriction endonucleases cut the DNA strand a little away from the centre of the palindromic site.

In the light of the above statements, choose the most appropriate answer from the options given below:

  • A
    Both Statement I and Statement II are incorrect
  • B
    Statement I is correct but Statement II is incorrect
  • C
    Statement I is incorrect but Statement II is correct
  • Correct answer
    D
    Both Statement I and Statement II are correct

Solution

Statement I: Restriction endonucleases do recognise unique sequences to cut the DNA. These sequences are arranged in the form of a palindrome.

So, statement I is correct.

Statement II: Restriction endonucleases cut the DNA strand a little away from the centre of the palindromic site. This helps generate sticky ends.

So, statement II is correct.

Option 4 is correct.

Note: Statement II is correct as per NCERT but is not correct scientifically as a general statement for restriction endonucleases.

Hence, the correct answer is option: 'D'.

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