Q75 / 200 · MHT CET - Medical 2026 (23 April Shift 1) · Biology

Given below are two statements about the oxygen dissociation curve.
Statement (I): The relationship between HbO$_2$ saturation and oxygen tension (ppO$_2$) is called oxygen dissociation curve.
Statement (II): Oxygen dissociation curve shifts towards the right due to decrease in H$^+$ concentration and decrease in temperature.
In light of the above statements, choose the most appropriate answer from the options given below.

  • A
    Both Statement (I) and Statement (II) are correct.
  • B
    Both Statement (I) and Statement (II) are incorrect.
  • Correct answer
    C
    Statement (I) is correct but Statement (II) is incorrect.
  • D
    Statement (I) is incorrect but Statement (II) is correct.

Solution

Statement (I) is correct. The oxygen dissociation curve is a graphical representation of the relationship between the partial pressure of oxygen (pO$_2$) and the percentage saturation of hemoglobin with oxygen.

Statement (II) is incorrect. The oxygen dissociation curve shifts to the right when there is a decrease in oxygen affinity of hemoglobin. This occurs due to an increase in H$^+$ concentration (decrease in pH), an increase in partial pressure of CO$_2$ (pCO$_2$), and an increase in temperature. A decrease in H$^+$ concentration and a decrease in temperature would shift the curve to the left.

Answer: Statement (I) is correct but Statement (II) is incorrect.

Hence, the correct answer is option: 'C'.

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