Q15 / 67 · NEST (NISER) 2021 (Session 1) · Biology

Escherichia coli strains (I-IV) with mutations in the lac operon were studied for $\beta$ galactosidase activity, followed by measuring its mRNA and protein levels (Graphs). The arrow indicates the time of addition of a compound (namely IPTG) that induces the lac operon. Based on the results, the correct option(s) is(are)
Figure

  • A
    In strain-I, the lac operon is not regulated and $\beta$-galactosidase is inactive.
  • B
    In strain-II, the lac operon is not regulated and $\beta$-galactosidase is inactive.
  • Correct answer
    C
    In strain-IV, the lac operon is not regulated and $\beta$-galactosidase protein is not produced.
  • Correct answer
    D
    In strain-III, the lac operon is regulated and $\beta$-galactosidase is active.

Hence, the correct answer is options: 'C', 'D'.

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