During evolution, the mitochondrial genome lost many genes, and some of these got incorporated into the nuclear genome. Proteins synthesized in the cytoplasm are transported to various destinations, including some that are secreted outside the cell. Based on the transport and localization of proteins within cells, the correct option(s) is(are)

• A

  Proteins secreted outside the cell are not transported via the endoplasmic reticulum.
• B

  All proteins with mitochondrial function are synthesized inside the mitochondria.
• Correct answer
  C

  All the proteins having nuclear function are synthesized in the cytoplasm.
• Correct answer
  D

  Some nuclear encoded proteins are transported to the mitochondria.

Hence, the correct answer is options: 'C', 'D'.