Q81 / 200 · MHT CET - Medical 2026 (24 April Shift 1) · Biology
Along with Histone like DNA binding proteins which enzyme maintains supercoiled state in packaging of DNA in prokaryotes?
- ADNA polymerase and RNA primase
- BDNA ligase and helicase
- Correct answerCDNA gyrase and topoisomerase I
- DPhosphorylase and RNA polymerase
Solution
In prokaryotes, the DNA is organized into large loops held by histone-like DNA binding proteins. The supercoiled state of the circular DNA is maintained by the enzymes DNA gyrase (a type of topoisomerase II) and topoisomerase I.
DNA gyrase introduces negative supercoils into the DNA, whereas topoisomerase I relaxes them. Together, they balance and maintain the required supercoiled state for compact packaging of the nucleoid.
Answer: DNA gyrase and topoisomerase I
DNA gyrase introduces negative supercoils into the DNA, whereas topoisomerase I relaxes them. Together, they balance and maintain the required supercoiled state for compact packaging of the nucleoid.
Answer: DNA gyrase and topoisomerase I
Hence, the correct answer is option: 'C'.