Q32 / 200 · MHT CET - Medical 2026 (26 April Shift 1) · Biology

Given below are two statements:
Statement I - Avery, Mc Carty and Mac Leod first evidenced to prove the DNA is a genetic material.
Statement II - Hershey and Chase used Streptococcus pneumoniae to confirm the nature of the transforming principle.
In the light of the above statements, choose the correct option given below:

  • A
    Both statement I and statement II are correct.
  • B
    Both statement I and statement II are incorrect.
  • Correct answer
    C
    Statement I is correct but statement II is incorrect.
  • D
    Statement I is incorrect but statement II is correct.

Solution

Statement I is correct because Oswald Avery, Colin MacLeod, and Maclyn McCarty (1933-1944) were the first to provide biochemical evidence that DNA is the genetic material. They determined the biochemical nature of the transforming principle in Griffith's experiment and concluded that DNA is the hereditary material.

Statement II is incorrect because Alfred Hershey and Martha Chase (1952) used bacteriophages (T2 phage) and Escherichia coli to unequivocally prove that DNA is the genetic material. Streptococcus pneumoniae was used by Frederick Griffith in his transformation experiments.

Answer: Statement I is correct but statement II is incorrect.

Hence, the correct answer is option: 'C'.

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