A graph showing the effect of substrate concentration $[\mathrm{S}]$ on enzyme activity is given below. The correct statement(s) is/are:

• A

  The reaction velocity reaches a maximum at low substrate concentration.
• Correct answer
  B

  If a competitive inhibitor binds to the active site of the enzyme, it would not change the maximum velocity.
• Correct answer
  C

  If an inhibitor that closely resembles the substrate binds to the active site of the enzyme, it would increase the $\mathrm{K}_{\mathrm{m}}$ of the reaction.
• D

  In the presence of a competitive inhibitor, increasing substrate concentration will not affect enzyme activity.

Hence, the correct answer is options: 'B', 'C'.