Q9 / 200 · MHT CET - Medical 2026 (25 April Shift 2) · Biology
Which of the following statement is correct?
- Correct answerAPepsin acts on protein in acidic medium.
- BTrypsin acts on protein in acidic medium.
- CPepsinogen is converted to pepsin by enterokinase.
- DRelease of gastric juice from stomach is stimulated by secretin.
Solution
Pepsin is a proteolytic enzyme secreted by the gastric glands of the stomach in its inactive form, pepsinogen. It is activated into pepsin by the highly acidic medium provided by hydrochloric acid (HCl) at a pH of approximately $1.8$. Pepsin then acts on proteins to convert them into proteoses and peptones.
Trypsin acts on proteins in an alkaline medium in the small intestine.
Pepsinogen is converted to pepsin by HCl, whereas enterokinase converts trypsinogen into active trypsin.
The release of gastric juice is stimulated by the hormone gastrin, while secretin inhibits gastric secretion and stimulates the secretion of water and bicarbonate from the pancreas.
Answer: Pepsin acts on protein in acidic medium.
Trypsin acts on proteins in an alkaline medium in the small intestine.
Pepsinogen is converted to pepsin by HCl, whereas enterokinase converts trypsinogen into active trypsin.
The release of gastric juice is stimulated by the hormone gastrin, while secretin inhibits gastric secretion and stimulates the secretion of water and bicarbonate from the pancreas.
Answer: Pepsin acts on protein in acidic medium.
Hence, the correct answer is option: 'A'.