Q187 / 200 · NEET 2022 (Phase 2) · Zoology

Which of the following reasons in mainly responsible for graft rejection in transplantation of organs?

A
Inability of recipient to differentiate between 'self and 'non-self' tissues/cells
B
Humoral immune response only
C
Auto-immune response
Correct answer
D
Cell-mediated response

Solution

During organ transplantation, the graft rejection takes place due to cell mediated response, in which T-cell controls the identification of Self from Non-self. This rejection can be prevented by Immuno-suppressive agent i.e., Cyclosporin-A.

Hence, the correct answer is option: 'D'.

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