Q177 / 180 · JIPMER 2018 · Zoology

Which is present at $5^{\prime}$ end of eukaryotic mRNA?

  • A
    $Poly-A tail$
  • B
    $Modified C at 5'$
  • Correct answer
    C
    $7 mG$
  • D
    $Poly-C$

Solution

At the 5' end of eukaryotic mRNA, 7 mG (7-methyl guanosine) is present. In eukaryotes, primary transcript is often larger than the functional RNAs. Therefore, post-transcription processing is required to convert primary transcript of all types of RNAs into functional RNAs. It is of four types; cleavage, splicing, terminal additional and nucleotide modification. The terminal additions include capping and tailing. In capping, 7 mG is added to $5^{\prime}$ end of mRNA. In tailing, polyadenylation occurs which is addition of poly (A) tail to $3^{\prime}$ end of mRNA.

Hence, the correct answer is option: 'C'.

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