Q152 / 199 · NEET 2008 (Mains) · Zoology

What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?

  • A
    Enterokinase will not be released from the duodenal mucosa and so trypsinogen is not converted to trypsin
  • B
    Gastric juice will be deficient in chymosin
  • C
    Gastric juice will be deficient in pepsinogen
  • Correct answer
    D
    In the absence of $\mathrm{HCl}$ secretion, inactive pepsinogen is not converted into the active enzyme pepsin.

Solution

Parietal cells/oxyntic cells, their function is to secrete $\mathrm{HCl}$ and Castle's intrinsic factor. Pepsinogen, is converted into active pepsin by $\mathrm{HCl}$, i.e. by change in $\mathrm{pH}$.

Hence, the correct answer is option: 'D'.

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