Q23 / 180 · JIPMER 2015 · Botany

The enzyme hexokinase which catalysis glucose to a glucose-6-phosphate in glycolysis is inhibited by glucose-6-phosphate. This is an example of I. competitive inhibition II. non-competitive inhibition III. feedback allosteric inhibition Which of the above statements is/are correct?

  • A
    I and II
  • B
    I and III
  • Correct answer
    C
    Only III
  • D
    All of these

Solution

Hexokinase catalyses the phosphorylation of hexose in general and is found in all cells that metabolise glucose. It has low $K_m$ (high affinity, strong bonding) with glucose in such a way that it is active at low glucose concentration. It shows allosteric feed beat inhibition by to product glucose-6-phosphate.

Hence, the correct answer is option: 'C'.

Relevant Questions