Q23 / 200 · MHT CET - Medical 2026 (23 April Shift 1) · Biology
Select the INCORRECT statement with respect to coding strand.
- AIt is also known as sense strand.
- BThe terminator is located at 3' end of coding strand.
- CThe nucleotide sequence of this strand is the same as in RNA, except that RNA contains uracil in place of thymine.
- Correct answerDThe nucleotide sequence of this strand is the same as in the template strand with 3' $\rightarrow$ 5' polarity.
Solution
The coding strand is the DNA strand whose base sequence corresponds to the base sequence of the RNA transcript produced, with thymine replaced by uracil. It is also known as the sense strand or non-template strand.
The promoter is located towards the 5' end (upstream) of the structural gene with respect to the coding strand, while the terminator is located towards the 3' end (downstream) of the coding strand.
The nucleotide sequence of the coding strand is complementary to the template strand, not the same as it. Therefore, the statement that its sequence is the same as the template strand is incorrect.
Answer: The nucleotide sequence of this strand is the same as in the template strand with 3' $\rightarrow$ 5' polarity.
The promoter is located towards the 5' end (upstream) of the structural gene with respect to the coding strand, while the terminator is located towards the 3' end (downstream) of the coding strand.
The nucleotide sequence of the coding strand is complementary to the template strand, not the same as it. Therefore, the statement that its sequence is the same as the template strand is incorrect.
Answer: The nucleotide sequence of this strand is the same as in the template strand with 3' $\rightarrow$ 5' polarity.
Hence, the correct answer is option: 'D'.