Nitrogenous waste which is less toxic, soluble in water and formed during ornithine cycle is ----------------.

Ammonia is highly toxic and requires a large amount of water for its elimination.

Uric acid is the least toxic nitrogenous waste and is insoluble in water, being excreted as a paste or pellet.

Urea is less toxic than ammonia, is soluble in water, and is synthesized in the liver through the ornithine cycle (also known as the urea cycle) from ammonia and carbon dioxide.

Therefore, the nitrogenous waste that fits all the given criteria is urea.

Answer: Urea