Q15 / 230 · NTA Abhyas (NEET) 2020 · Zoology · Body Fluids and Circulation

Mechanism of blood clotting is given below:

An injury or a trauma stimulates the platelets in the blood to release certain factors which activate the mechanism of coagulation. An enzyme complex, ______P_______ is formed by a series of linked enzymic reactions (______Q_______process) involving a number of factors present in the plasma in an inactive state. This enzyme complex is required for formation of______R_______. _____S_______ ions play a very important role in clotting.

Identify the correct option that represents P, Q, R, and S.

  • A
    P Q R S
    thrombokinase inhibitory prothrombin magnesium
  • B
    P Q R S
    prothrombin cascade thrombin magnesium
  • C
    P Q R S
    thrombin cascade thrombokinase calcium
  • Correct answer
    D
    P Q R S
    thrombokinase cascade thrombin calcium

Solution

Mechanism of blood coagulation or clotting

A. Injury or trauma results in:

I. Stimulation of platelets → Release of certain factors that activate the mechanism of coagulation.

II. Damaged tissues → Release of certain factors that can also initiate coagulation.

B. A series of linked enzymic reactions (cascade process) that involves a number of clotting factors present in the plasma in an inactive state is initiated that finally results in the formation of an enzyme complex - Thrombokinase.

C. Prothrombin ---------- Thrombokinase-------- → Thrombin

D. Fibrinogens in the plasma ---------- Thrombin-------- → Fibrins

- Calcium ions are very important for clotting.

Hence, the correct answer is option: 'D'.

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