Q7 / 80 · NEST (NISER) 2024 (Session 1) · Biology
In the given pedigree, circles represent females and squares represent males. Filled shapes indicate affected individuals, while unfilled shapes indicate unaffected individuals. Based on the pedigree analysis, consider the statements (i) to (iv)

(i) If the inheritance pattern is autosomal recessive, then the individual III-8 is a carrier of the disease.
(ii) If the inheritance pattern is X-linked recessive, then the individuals II-6 and III-7 are carriers of the disease.
(iii) Individuals I-1 and I-2 are homozygous for the allele under study.
(iv) If the inheritance pattern is autosomal recessive, then individuals III-2 and IV-1 must be carriers of the disease.
The correct combination of statements is:

(i) If the inheritance pattern is autosomal recessive, then the individual III-8 is a carrier of the disease.
(ii) If the inheritance pattern is X-linked recessive, then the individuals II-6 and III-7 are carriers of the disease.
(iii) Individuals I-1 and I-2 are homozygous for the allele under study.
(iv) If the inheritance pattern is autosomal recessive, then individuals III-2 and IV-1 must be carriers of the disease.
The correct combination of statements is:
- Ai, ii and iv
- Correct answerBi and ii
- Cii, iii, iv
- Dii, iv
Hence, the correct answer is option: 'B'.