Q44 / 240 · KCET 2026 · Biology
Given below are two statements
Statement-I: Adenosine deaminase is crucial for the immune system to function.
Statement-II: Adenosine deaminase deficiency can be cured only by bone marrow transplantation.
In the light of the above statements, choose the correct answer from the options given below.
Statement-I: Adenosine deaminase is crucial for the immune system to function.
Statement-II: Adenosine deaminase deficiency can be cured only by bone marrow transplantation.
In the light of the above statements, choose the correct answer from the options given below.
- ABoth Statement I and Statement II are true
- BBoth Statement I and Statement II are false
- Correct answerCStatement I is true, but Statement II is false
- DStatement I is false, but Statement II is true
Solution
Adenosine deaminase (ADA) is an enzyme that is essential for the proper functioning of the immune system. Its deficiency causes Severe Combined Immunodeficiency (SCID). Thus, Statement-I is true.
ADA deficiency can be treated by enzyme replacement therapy, bone marrow transplantation, and gene therapy. Bone marrow transplantation and enzyme replacement therapy are not completely curative. A permanent cure is possible if gene therapy is administered at early embryonic stages. Therefore, the claim that it can be cured only by bone marrow transplantation is incorrect. Thus, Statement-II is false.
Answer: Statement I is true, but Statement II is false
ADA deficiency can be treated by enzyme replacement therapy, bone marrow transplantation, and gene therapy. Bone marrow transplantation and enzyme replacement therapy are not completely curative. A permanent cure is possible if gene therapy is administered at early embryonic stages. Therefore, the claim that it can be cured only by bone marrow transplantation is incorrect. Thus, Statement-II is false.
Answer: Statement I is true, but Statement II is false
Hence, the correct answer is option: 'C'.