Q46 / 200 · MHT CET - Medical 2026 (24 April Shift 2) · Biology

During lactic acid fermentation, pyruvic acid is reduced to lactic acid using one proton and two electrons from ________________.

  • Correct answer
    A
    $\text{NADH} + \text{H}^+$ produced during glycolysis.
  • B
    $\text{FADH}_2$ produced in Krebs cycle.
  • C
    Acetyl CoA.
  • D
    Water.

Solution

During lactic acid fermentation, pyruvic acid is reduced to lactic acid by the enzyme lactate dehydrogenase.

The reducing agent for this reaction is $\text{NADH} + \text{H}^+$, which is produced during the oxidation steps of glycolysis.

In this process, $\text{NADH} + \text{H}^+$ donates electrons and a proton to pyruvic acid, getting reoxidized to $\text{NAD}^+$, which is then reused in glycolysis.

Answer: $\text{NADH} + \text{H}^+$ produced during glycolysis.

Hence, the correct answer is option: 'A'.

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