Q200 / 200 · NEET 2005 · Zoology
At a particular locus, frequency of $A$ allele is 0.6 and that of a is 0.4 . What would be the frequency of heterozygotes in a random mating population at equilibrium?
- A0.36
- B0.16
- C0.24
- Correct answerD0.48
Solution
In a stable population, for a gene with two alleles, 'A' (dominant) and 'a' (recessive),
the frequency of ' $\mathrm{A}^{\prime}=\mathrm{p}$
the frequency of ' $a$ ' $=q$,
According Hardy-Weinberg equation:
$$
\mathrm{p}^2+2 p q+q^2=1
$$
where $\mathrm{p}^2=$ Frequency of $\mathrm{A}$ (homozygous dominant) individuals $\mathrm{q}^2=$ Frequency of aa (homozygous recessive) individuals
$2 \mathrm{pq}=$ Frequency of $\mathrm{Aa}$ (heterozygous) individuals.
$$
\begin{aligned}
& \therefore 2 \mathrm{pq}(\text { frequency of heterozygote })= \\
& 2 \times 0.6 \times 0.4=0.48
\end{aligned}
$$
Hence, the correct answer is option: 'D'.