Q20 / 370 · NTA Abhyas (NEET) 2020 · Zoology · Human Health and Diseases

Antibody molecule is Y shaped. The two tips of this Y shaped molecule bind to antigen through which type of interaction/bond?

  • Correct answer
    A
    Non-covalent interaction
  • B
    Disulfide bonds
  • C
    Covalent interaction
  • D
    Peptide bond

Solution

The typical structure of immunoglobulin or antibody is Y shaped and is represented as H2L2. This means it consists of two heavy chains and two light chains. These chains are polypeptide chains and because of difference in weights one is termed as heavy and other is termed as light. Both these chains are linked by disulphide bonds. Each chain consists of two regions: constant region or FC i.e. fragment crystallizable and variable region or Fab i.e. fragment for antigen-binding region. Thus the variable region consists of antigen-binding site that is a part of heavy and light chains. Antigens are attached to antibodies through non-covalent bonds.

Hence, the correct answer is option: 'A'.

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